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Effect of Interior Loop Length on the Thermal Stability and pK(a) of i-Motif DNA

The four-stranded i-motif (iM) conformation of cytosine-rich DNA has importance to a wide variety of biochemical systems that range from its use in nanomaterials to a potential role in oncogene regulation. An iM is stabilized by acidic pH that allows hemiprotonated cytidines to form a C•C(+) base pa...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Reilly, Samantha M., Morgan, Rhianna K., Brooks, Tracy A., Wadkins, Randy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4630671/
https://ncbi.nlm.nih.gov/pubmed/25619229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5014722
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