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Making sense of G-quadruplex and i-motif functions in oncogene promoters

The presence and biological importance of DNA secondary structures in eukaryotic promoters are becoming increasingly recognized among chemists and biologists as bioinformatics, in vitro, and in vivo evidence for these structures in the c-Myc, c-Kit, KRAS, PDGF-A, hTERT, Rb, RET and Hif-1α promoters...

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Main Authors: Brooks, Tracy A., Kendrick, Samantha, Hurley, Laurence
格式: Artigo
語言:Inglês
出版: 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971675/
https://ncbi.nlm.nih.gov/pubmed/20670278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07759.x
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