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Making sense of G-quadruplex and i-motif functions in oncogene promoters

The presence and biological importance of DNA secondary structures in eukaryotic promoters are becoming increasingly recognized among chemists and biologists as bioinformatics, in vitro, and in vivo evidence for these structures in the c-Myc, c-Kit, KRAS, PDGF-A, hTERT, Rb, RET and Hif-1α promoters...

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Autores principales: Brooks, Tracy A., Kendrick, Samantha, Hurley, Laurence
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971675/
https://ncbi.nlm.nih.gov/pubmed/20670278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07759.x
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