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Formation of pseudo-symmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene

A polypurine (guanine)/polypyrimidine (cytosine)–rich sequence within the proximal promoter region of the human RET oncogene has been shown to be essential for RET basal transcription. Specifically, the polypurine-rich strand within this region consists of five consecutive runs of guanines, which is...

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Detalhes bibliográficos
Main Authors: Guo, Kexiao, Pourpak, Alan, Beetz-Rogers, Kara, Gokhale, Vijay, Sun, Daekyu, Hurley, Laurence H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566970/
https://ncbi.nlm.nih.gov/pubmed/17672459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja072185g
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