Gene Expression in the Etiology of Schizophrenia

Por Bray, Nicholas J.
Publicado em 2008

Allelic differences in nuclear protein binding at a genome-wide significant risk variant for schizophrenia in ZNF804A

Por Hill, Matthew J., Bray, Nicholas J.
Publicado em 2011

Translating Genetic Risk Loci Into Molecular Risk Mechanisms for Schizophrenia

Por Bray, Nicholas J., Hill, Matthew J.
Publicado no Schizophr Bull (2016)

Investigating schizophrenia in a “dish”: possibilities, potential and limitations

Por BRAY, NICHOLAS J., KAPUR, SHITIJ, PRICE, JACK
Publicado em 2012

5-hydroxymethylcytosine is highly dynamic across human fetal brain development

Por Spiers, Helen, Hannon, Eilis, Schalkwyk, Leonard C., Bray, Nicholas J., Mill, Jonathan
Publicado no BMC Genomics (2017)

Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain

Por Duarte, Rodrigo R. R., Troakes, Claire, Nolan, Matthew, Srivastava, Deepak P., Murray, Robin M., Bray, Nicholas J.
Publicado no Am J Med Genet B Neuropsychiatr Genet (2016)

Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells

Por Hill, Matthew J., Donocik, Jacek G., Nuamah, Rosamond A., Mein, Charles A., Sainz-Fuertes, Ricardo, Bray, Nicholas J.
Publicado em 2014

Knockdown of the schizophrenia susceptibility gene TCF4 alters gene expression and proliferation of progenitor cells from the developing human neocortex

Por Hill, Matthew J., Killick, Richard, Navarrete, Katherinne, Maruszak, Aleksandra, McLaughlin, Gemma M., Williams, Brenda P., Bray, Nicholas J.
Publicado no J Psychiatry Neurosci (2017)

A Haplotype Implicated in Schizophrenia Susceptibility Is Associated with Reduced COMT Expression in Human Brain

Por Bray, Nicholas J., Buckland, Paul R., Williams, Nigel M., Williams, Hywel J., Norton, Nadine, Owen, Michael J., O’Donovan, Michael C.
Publicado em 2003

Methylomic trajectories across human fetal brain development

Por Spiers, Helen, Hannon, Eilis, Schalkwyk, Leonard C., Smith, Rebecca, Wong, Chloe C.Y., O’Donovan, Michael C., Bray, Nicholas J., Mill, Jonathan
Publicado no Genome Res (2015)

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Por Pidsley, Ruth, Viana, Joana, Hannon, Eilis, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Mechawar, Naguib, Turecki, Gustavo, Schalkwyk, Leonard C, Bray, Nicholas J, Mill, Jonathan
Publicado no Genome Biol (2014)

Effects of cis-regulatory variation differ across regions of the adult human brain

Por Buonocore, Federica, Hill, Matthew J., Campbell, Colin D., Oladimeji, Paul B., Jeffries, Aaron R., Troakes, Claire, Hortobagyi, Tibor, Williams, Brenda P., Cooper, Jonathan D., Bray, Nicholas J.
Publicado em 2010

Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions

Por Hannon, Eilis, Spiers, Helen, Viana, Joana, Pidsley, Ruth, Burrage, Joe, Murphy, Therese M, Troakes, Claire, Turecki, Gustavo, O’Donovan, Michael C., Schalkwyk, Leonard C., Bray, Nicholas J., Mill, Jonathan
Publicado no Nat Neurosci (2015)

Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure

Por Deans, P.J. Michael, Raval, Pooja, Sellers, Katherine J., Gatford, Nicholas J.F., Halai, Sanjay, Duarte, Rodrigo R.R., Shum, Carole, Warre-Cornish, Katherine, Kaplun, Victoria E., Cocks, Graham, Hill, Matthew, Bray, Nicholas J., Price, Jack, Srivastava, Deepak P.
Publicado no Biol Psychiatry (2017)

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia

Por Georgieva, Lyudmila, Moskvina, Valentina, Peirce, Tim, Norton, Nadine, Bray, Nicholas J., Jones, Lesley, Holmans, Peter, MacGregor, Stuart, Zammit, Stanley, Wilkinson, Jennifer, Williams, Hywel, Nikolov, Ivan, Williams, Nigel, Ivanov, Dobril, Davis, Kenneth L., Haroutunian, Vahram, Buxbaum, Joseph D., Craddock, Nick, Kirov, George, Owen, Michael J., O’Donovan, Michael C.
Publicado em 2006