Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

BACKGROUND: Schizophrenia is a severe neuropsychiatric disorder that is hypothesized to result from disturbances in early brain development. There is mounting evidence to support a role for developmentally regulated epigenetic variation in the molecular etiology of the disorder. Here, we describe a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Pidsley, Ruth, Viana, Joana, Hannon, Eilis, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Mechawar, Naguib, Turecki, Gustavo, Schalkwyk, Leonard C, Bray, Nicholas J, Mill, Jonathan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262979/
https://ncbi.nlm.nih.gov/pubmed/25347937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0483-2
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