Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions

Genetic association studies provide evidence for a substantial polygenic component to schizophrenia, although the neurobiological mechanisms underlying the disorder remain largely undefined. Building on recent studies supporting a role for developmentally regulated epigenetic variation in the molecu...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Viana, Joana, Hannon, Eilis, Dempster, Emma, Pidsley, Ruth, Macdonald, Ruby, Knox, Olivia, Spiers, Helen, Troakes, Claire, Al-Saraj, Safa, Turecki, Gustavo, Schalkwyk, Leonard C., Mill, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351932/
https://ncbi.nlm.nih.gov/pubmed/28011714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw373
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