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Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain

Chromosome 10q24.32‐q24.33 is one of the most robustly supported risk loci to emerge from genome‐wide association studies (GWAS) of schizophrenia. However, extensive linkage disequilibrium makes it difficult to distinguish the actual susceptibility gene(s) at the locus, limiting its value for improv...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Duarte, Rodrigo R. R., Troakes, Claire, Nolan, Matthew, Srivastava, Deepak P., Murray, Robin M., Bray, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988385/
https://ncbi.nlm.nih.gov/pubmed/27004590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32445
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