Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain

Chromosome 10q24.32‐q24.33 is one of the most robustly supported risk loci to emerge from genome‐wide association studies (GWAS) of schizophrenia. However, extensive linkage disequilibrium makes it difficult to distinguish the actual susceptibility gene(s) at the locus, limiting its value for improv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Med Genet B Neuropsychiatr Genet
Prif Awduron: Duarte, Rodrigo R. R., Troakes, Claire, Nolan, Matthew, Srivastava, Deepak P., Murray, Robin M., Bray, Nicholas J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988385/
https://ncbi.nlm.nih.gov/pubmed/27004590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32445
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