Bosutinib in chronic myeloid leukemia: patient selection and perspectives

Por Isfort, Susanne, Brümmendorf, Tim H
Publicado no J Blood Med (2018)

Practical management of toxicities associated with bosutinib in patients with Philadelphia chromosome-positive chronic myeloid leukemia

Por Khoury, H J, Gambacorti-Passerini, C, Brümmendorf, T H
Publicado no Ann Oncol (2018)

Dynamics of Resistance Development to Imatinib under Increasing Selection Pressure: A Combination of Mathematical Models and In Vitro Data

Por Werner, Benjamin, Lutz, David, Brümmendorf, Tim H., Traulsen, Arne, Balabanov, Stefan
Publicado em 2011

Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

Por Bennemann Karla, Galm Oliver, Wilop Stefan, Schubert Claudia, Brümmendorf Tim H, Jost Edgar
Publicado em 2012-08-01

Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia

Por Oing, Christoph, Jost, Edgar, Dahl, Edgar, Wilop, Stefan, Brümmendorf, Tim H., Galm, Oliver
Publicado em 2011

Epigenetic dysregulation of secreted frizzled-related proteins in myeloproliferative neoplasms complements the JAK2V617F-mutation

Por Bennemann, Karla, Galm, Oliver, Wilop, Stefan, Schubert, Claudia, Brümmendorf, Tim H, Jost, Edgar
Publicado em 2012

Asymmetric Cell Divisions Sustain Long-Term Hematopoiesis from Single-sorted Human Fetal Liver Cells

Por Brummendorf, Tim H., Dragowska, Wieslawa, Zijlmans, J.Mark J.M., Thornbury, Gayle, Lansdorp, Peter M.
Publicado em 1998

MicroRNA expression profiles of serum from patients before and after chemotherapy

Por Diener, Yvonne, Walenda, Thomas, Jost, Edgar, Brümmendorf, Tim H., Bosio, Andreas, Wagner, Wolfgang, Bissels, Ute
Publicado no Genom Data (2015)

Perioperative intravenous immunoglobulin treatment in a patient with severe acquired von Willebrand syndrome: case report and review of the literature

Por Jennes, Eva, Guggenberger, Dorothee, Zotz, Rainer, Thompson, Lora, Brümmendorf, Tim H., Koschmieder, Steffen, Jost, Edgar
Publicado no Clin Case Rep (2017)

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

Por Han, Lijuan, Schubert, Claudia, Köhler, Johanna, Schemionek, Mirle, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Chatain, Nicolas
Publicado no J Hematol Oncol (2016)

Telomere Fluorescence Measurements in Granulocytes and T Lymphocyte Subsets Point to a High Turnover of Hematopoietic Stem Cells and Memory T Cells in Early Childhood

Por Rufer, Nathalie, Brümmendorf, Tim H., Kolvraa, Steen, Bischoff, Claus, Christensen, Kaare, Wadsworth, Louis, Schulzer, Michael, Lansdorp, Peter M.
Publicado em 1999

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

Por Hennigs, Jan K, Keller, Gunhild, Baumann, Hans Jörg, Honecker, Friedemann, Kluge, Stefan, Bokemeyer, Carsten, Brümmendorf, Tim H, Klose, Hans
Publicado em 2011

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

Por Werner, Benjamin, Beier, Fabian, Hummel, Sebastian, Balabanov, Stefan, Lassay, Lisa, Orlikowsky, Thorsten, Dingli, David, Brümmendorf, Tim H, Traulsen, Arne
Publicado no eLife (2015)

Combined Population Dynamics and Entropy Modelling Supports Patient Stratification in Chronic Myeloid Leukemia

Por Brehme, Marc, Koschmieder, Steffen, Montazeri, Maryam, Copland, Mhairi, Oehler, Vivian G., Radich, Jerald P., Brümmendorf, Tim H., Schuppert, Andreas
Publicado no Sci Rep (2016)

Serum of myeloproliferative neoplasms stimulates hematopoietic stem and progenitor cells

Por Lubberich, Richard K., Walenda, Thomas, Goecke, Tamme W., Strathmann, Klaus, Isfort, Susanne, Brümmendorf, Tim H., Koschmieder, Steffen, Wagner, Wolfgang
Publicado no PLoS One (2018)

Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part

Por Vermorken, J B, Guigay, J, Mesia, R, Trigo, J M, Keilholz, U, Kerber, A, Bethe, U, Picard, M, Brummendorf, T H
Publicado em 2011

DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia

Por Božić, Tanja, Lin, Qiong, Frobel, Joana, Wilop, Stefan, Hoffmann, Melanie, Müller-Tidow, Carsten, Brümmendorf, Tim H., Jost, Edgar, Wagner, Wolfgang
Publicado no Clin Epigenetics (2015)

Development of a disease-specific quality of life questionnaire for patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria (QLQ-AA/PNH)—report on phases I and II...

Por Groth, Martha, Singer, Susanne, Niedeggen, Cathrin, Petermann-Meyer, Andrea, Röth, Alexander, Schrezenmeier, Hubert, Höchsmann, Britta, Brümmendorf, Tim H., Panse, Jens
Publicado no Ann Hematol (2016)

The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients

Por Schubert, Claudia, Chatain, Nicolas, Braunschweig, Till, Schemionek, Mirle, Feldberg, Kristina, Hoffmann, Melanie, Dufva, Olli, Mustjoki, Satu, Brümmendorf, Tim H., Koschmieder, Steffen
Publicado no Oncotarget (2017)

Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas

Por Ventura Ferreira, Monica S., Crysandt, Martina, Braunschweig, Till, Jost, Edgar, Voss, Barbara, Bouillon, Anne-Sophie, Knuechel, Ruth, Brümmendorf, Tim H., Beier, Fabian
Publicado no Int J Mol Sci (2018)