Dabigatran, a direct thrombin inhibitor, blocks differentiation of normal fibroblasts to a myofibroblast phenotype and demonstrates anti-fibrotic effects on scleroderma lung fibrob...

Por Bogatkevich, Galina S., Ludwicka-Bradley, Anna, Silver, Richard M.
Publicado em 2009

Coagulation and Autoimmunity in Scleroderma Interstitial Lung Disease

Por Ludwicka-Bradley, Anna, Silver, Richard M., Bogatkevich, Galina S.
Publicado em 2010

The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects

Por Bogatkevich, Galina S., Highland, Kristin B., Akter, Tanjina, Silver, Richard M.
Publicado em 2012

Rationale for Anticoagulant Therapy of Pulmonary Fibrosis

Por Bogatkevich, Galina S., Nietert, Paul J., Silver, Richard M., Highland, Kristin B.
Publicado em 2014

Establishment of an indirect ELISA for detection of the novel antifibrotic peptide M10

Por Akter, Tanjina, Atanelishvili, Ilia, Noguchi, Atsushi, Silver, Richard M., Bogatkevich, Galina S.
Publicado no PLoS One (2017)

Racial Differences between Blacks and Whites with Systemic Sclerosis

Por Silver, Richard M., Bogatkevich, Galina, Tourkina, Elena, Nietert, Paul J., Hoffman, Stanley
Publicado em 2012

Proteomic analysis of CTGF-activated lung fibroblasts: identification of IQGAP1 as a key player in lung fibroblast migration

Por Bogatkevich, Galina S., Ludwicka-Bradley, Anna, Singleton, C. Beth, Bethard, Jennifer R., Silver, Richard M.
Publicado em 2008

Thrombin Increases Lung Fibroblast Survival while Promoting Alveolar Epithelial Cell Apoptosis via the Endoplasmic Reticulum Stress Marker, CCAAT Enhancer–Binding Homologous Protei...

Por Atanelishvili, Ilia, Liang, Jun, Akter, Tanjina, Spyropoulos, Demetri D., Silver, Richard M., Bogatkevich, Galina S.
Publicado em 2014

Elevated Levels of Endothelin-1 in Hepatic Venous Blood Are Associated with Intrapulmonary Vasodilatation in Humans

Por Koch, David G., Bogatkevich, Galina, Ramshesh, Venkat, Lemasters, John J., Uflacker, Renan, Reuben, Adrian
Publicado no Dig Dis Sci (2011)

M10, a Caspase Cleavage Product of the Hepatocyte Growth Factor Receptor, Interacts with Smad2 and Demonstrates Anti-Fibrotic Properties in Vitro and in Vivo

Por Atanelishvili, Ilia, Shirai, Yuichiro, Akter, Tanjina, Buckner, Taylor, Noguchi, Atsushi, Silver, Richard M., Bogatkevich, Galina S.
Publicado no Transl Res (2015)

Anti-inflammatory and anti-fibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease

Por Bogatkevich, Galina S., Ludwicka-Bradley, Anna, Nietert, Paul J., Akter, Tanjina, van Ryn, Joanne, Silver, Richard M.
Publicado em 2011

D1398G Variant of MET Is Associated with Impaired Signaling of Hepatocyte Growth Factor in Alveolar Epithelial Cells and Lung Fibroblasts

Por Atanelishvili, Ilia, Shirai, Yuichiro, Akter, Tanjina, Noguchi, Atsushi, Ash, Kurt T., Misra, Suniti, Ghatak, Sibnath, Silver, Richard M., Bogatkevich, Galina S.
Publicado no PLoS One (2016)

Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

Por Ghatak, Shibnath, Hascall, Vincent C., Markwald, Roger R., Feghali-Bostwick, Carol, Artlett, Carol M., Gooz, Monika, Bogatkevich, Galina S., Atanelishvili, Ilia, Silver, Richard M., Wood, Jeanette, Thannickal, Victor J., Misra, Suniti
Publicado no J Biol Chem (2017)

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

Por Martyanov, Viktor, Kim, Grace-Hyun J., Hayes, Wendy, Du, Shuyan, Ganguly, Bishu J., Sy, Oumar, Lee, Sun Ku, Bogatkevich, Galina S., Schieven, Gary L., Schiopu, Elena, Marangoni, Roberta Gonçalves, Goldin, Jonathan, Whitfield, Michael L., Varga, John
Publicado no PLoS One (2017)

Overexpression of c-Met and CD44v6 Receptors Contributes to Autocrine TGF-β1 Signaling in Interstitial Lung Disease

Por Ghatak, Shibnath, Bogatkevich, Galina S., Atnelishvili, Ilia, Akter, Tanjina, Feghali-Bostwick, Carol, Hoffman, Stanley, Fresco, Victor M., Fuchs, John C., Visconti, Richard P., Markwald, Roger R., Padhye, Subhas B., Silver, Richard M., Hascall, Vincent C., Misra, Suniti
Publicado em 2014