Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive clinical syndrome of fatal outcome. The lack of information about the signaling pathways that sustain fibrosis and the myofibroblast phenotype has prevented the development of targeted therapies for IPF. Our previous study showed that isolated fib...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghatak, Shibnath, Hascall, Vincent C., Markwald, Roger R., Feghali-Bostwick, Carol, Artlett, Carol M., Gooz, Monika, Bogatkevich, Galina S., Atanelishvili, Ilia, Silver, Richard M., Wood, Jeanette, Thannickal, Victor J., Misra, Suniti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481559/
https://ncbi.nlm.nih.gov/pubmed/28389561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752469
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