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M10, a Caspase Cleavage Product of the Hepatocyte Growth Factor Receptor, Interacts with Smad2 and Demonstrates Anti-Fibrotic Properties in Vitro and in Vivo

Hepatocyte growth factor receptor, also known as cellular mesenchymal-epithelial transition factor (c-MET, MET), is an important antifibrotic molecule that protects various tissues, including lung, from injury and fibrosis. The intracellular cytoplasmic tail of MET contains a caspase-3 recognition m...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Atanelishvili, Ilia, Shirai, Yuichiro, Akter, Tanjina, Buckner, Taylor, Noguchi, Atsushi, Silver, Richard M., Bogatkevich, Galina S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789156/
https://ncbi.nlm.nih.gov/pubmed/26772959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2015.12.009
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