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Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

BACKGROUND: There are no effective treatments or validated clinical response markers in systemic sclerosis (SSc). We assessed imaging biomarkers and performed gene expression profiling in a single-arm open-label clinical trial of tyrosine kinase inhibitor dasatinib in patients with SSc-associated in...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Martyanov, Viktor, Kim, Grace-Hyun J., Hayes, Wendy, Du, Shuyan, Ganguly, Bishu J., Sy, Oumar, Lee, Sun Ku, Bogatkevich, Galina S., Schieven, Gary L., Schiopu, Elena, Marangoni, Roberta Gonçalves, Goldin, Jonathan, Whitfield, Michael L., Varga, John
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679625/
https://ncbi.nlm.nih.gov/pubmed/29121645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187580
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