Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

Por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado no Cell (2016)

PLD3 and PLD4 are single stranded acid exonucleases that regulate endosomal nucleic acid sensing

Por Gavin, Amanda L., Huang, Deli, Huber, Christoph, Mårtensson, Annica, Tardif, Virginie, Skog, Patrick D., Blane, Tanya R., Thinnes, Therese C., Osborn, Kent, Chong, Hayley S., Kargaran, Farnaz, Kimm, Phoebe, Zeitjian, Armen, Sielski, Rachel L., Briggs, Megan, Schulz, Sebastian R., Zarpellon, Alessandro, Cravatt, Benjamin, Pang, Ee Shan, Teijaro, John, de la Torre, Juan Carlos, O’Keeffe, Meredith, Hochrein, Hubertus, Damme, Markus, Teyton, Luc, Lawson, Brian R., Nemazee, David
Publicado no Nat Immunol (2018)

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

Por Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W., Del Moral-Sanchez, Ivan, McGuire, Andrew T., Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L.G.M., Freund, Natalia T., Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D., Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J., Pritchard, Laura K., Stanfield, Robyn L., Crispin, Max, Ward, Andrew B., Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P., Nemazee, David, Nussenzweig, Michel C., Wilson, Ian A., Sanders, Rogier W.
Publicado no J Exp Med (2017)