Activity of any class IA PI3K isoform can sustain cell proliferation and survival

Por Foukas, Lazaros C., Berenjeno, Inma M., Gray, Alexander, Khwaja, Asim, Vanhaesebroeck, Bart
Publicado em 2010

Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor

Por Berenjeno, Inma M., Guillermet-Guibert, Julie, Pearce, Wayne, Gray, Alexander, Fleming, Stewart, Vanhaesebroeck, Bart
Publicado em 2012

Phosphoproteomic comparison of Pik3ca and Pten signalling identifies the nucleotidase NT5C as a novel AKT substrate

Por Moniz, Larissa S., Surinova, Silvia, Ghazaly, Essam, Velasco, Lorena Gonzalez, Haider, Syed, Rodríguez-Prados, Juan Carlos, Berenjeno, Inma M., Chelala, Claude, Vanhaesebroeck, Bart
Publicado no Sci Rep (2017)

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

Por Aksoy, Ezra, Taboubi, Salma, Torres, David, Delbauve, Sandrine, Hachani, Abderrahman, Whitehead, Maria A, Pearce, Wayne P, Berenjeno, Inma M, Nock, Gemma, Filloux, Alain, Beyaert, Rudi, Flamand, Veronique, Vanhaesebroeck, Bart
Publicado em 2012

Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling

Por Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles, Vanhaesebroeck, Bart
Publicado no Nat Commun (2017)

Somatic Activating Mutations in Pik3ca Cause Sporadic Venous Malformations in Mice and Humans

Por Castillo, Sandra D., Tzouanacou, Elena, Zaw-Thin, May, Berenjeno, Inma M., Parker, Victoria E.R., Chivite, Iñigo, Milà-Guasch, Maria, Pearce, Wayne, Solomon, Isabelle, Angulo-Urarte, Ana, Figueiredo, Ana M., Dewhurst, Robert E., Knox, Rachel G., Clark, Graeme R., Scudamore, Cheryl L., Badar, Adam, Kalber, Tammy L., Foster, Julie, Stuckey, Daniel J., David, Anna L., Phillips, Wayne A., Lythgoe, Mark F., Wilson, Valerie, Semple, Robert K., Sebire, Neil J., Kinsler, Veronica A., Graupera, Mariona, Vanhaesebroeck, Bart
Publicado no Sci Transl Med (2016)