Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy

Por Beraldi, Rosanna, Li, Xing, Martinez Fernandez, Almudena, Reyes, Santiago, Secreto, Frank, Terzic, Andre, Olson, Timothy M., Nelson, Timothy J.
Publicado em 2014

Inhibition of DNA Topoisomerase II Selectively Reduces the Threat of Tumorigenicity Following Induced Pluripotent Stem Cell-Based Myocardial Therapy

Por Wyles, Saranya P., Yamada, Satsuki, Oommen, Saji, Maleszewski, Joseph J., Beraldi, Rosanna, Martinez-Fernandez, Almudena, Terzic, Andre, Nelson, Timothy J.
Publicado em 2014

A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies

Por Geraets, Ryan D., Langin, Logan M., Cain, Jacob T., Parker, Camille M., Beraldi, Rosanna, Kovacs, Attila D., Weimer, Jill M., Pearce, David A.
Publicado no PLoS One (2017)

Genetic Ataxia Telangiectasia porcine model phenocopies the multisystemic features of the human disease

Por Beraldi, Rosanna, Meyerholz, David K., Savinov, Alexei, Kovács, Attila D., Weimer, Jill M., Dykstra, Jordan A., Geraets, Ryan D., Pearce, David A.
Publicado no Biochim Biophys Acta (2017)

Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells

Por Wyles, Saranya P., Li, Xing, Hrstka, Sybil C., Reyes, Santiago, Oommen, Saji, Beraldi, Rosanna, Edwards, Jessica, Terzic, Andre, Olson, Timothy M., Nelson, Timothy J.
Publicado no Hum Mol Genet (2016)

iPS Cell-Derived Cardiogenicity is Hindered by Sustained Integration of Reprogramming Transgenes

Por Martinez-Fernandez, Almudena, Nelson, Timothy J., Reyes, Santiago, Alekseev, Alexey E., Secreto, Frank, Perez-Terzic, Carmen, Beraldi, Rosanna, Sung, Hoon-Ki, Nagy, Andras, Terzic, Andre
Publicado no Circ Cardiovasc Genet (2014)

A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease

Por Beraldi, Rosanna, Chan, Chun-Hung, Rogers, Christopher S., Kovács, Attila D., Meyerholz, David K., Trantzas, Constantin, Lambertz, Allyn M., Darbro, Benjamin W., Weber, Krystal L., White, Katherine A.M., Rheeden, Richard V., Kruer, Michael C., Dacken, Brian A., Wang, Xiao-Jun, Davis, Bryan T., Rohret, Judy A., Struzynski, Jason T., Rohret, Frank A., Weimer, Jill M., Pearce, David A.
Publicado no Hum Mol Genet (2015)