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A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies
The Neuronal Ceroid Lipofuscinoses (NCLs), also known as Batten disease, result from mutations in over a dozen genes. Although, adults are susceptible, the NCLs are frequently classified as pediatric neurodegenerative diseases due to their greater pediatric prevalence. Initial clinical presentation...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5413059/ https://ncbi.nlm.nih.gov/pubmed/28464005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176526 |
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