Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.

Por Batty, Ian H, Fleming, Ian N, Downes, C Peter
Publicado em 2004

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Por Walker, Steven M, Leslie, Nick R, Perera, Nevin M, Batty, Ian H, Downes, C Peter
Publicado em 2004

Loss of PTEN selectively desensitises upstream IGF1 and insulin signalling

Por Lackey, Joe, Barnett, Jill, Davidson, Lindsay, Batty, Ian H., Leslie, Nick R., Downes, C. Peter
Publicado em 2007

The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2

Por Batty, Ian H., vanderKaay, Jeroen, Gray, Alex, Telfer, Joan F., Dixon, Miles J., Downes, C. Peter
Publicado em 2007

Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1

Por Fleming, Ian N., Batty, Ian H., Prescott, Alan R., Gray, Alex, Kular, Gursant S., Stewart, Hazel, Downes, C. Peter
Publicado em 2004

A Screen for Novel Phosphoinositide 3-kinase Effector Proteins

Por Dixon, Miles J., Gray, Alexander, Boisvert, François-Michel, Agacan, Mark, Morrice, Nicholas A., Gourlay, Robert, Leslie, Nicholas R., Downes, C. Peter, Batty, Ian H.
Publicado em 2011

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Por Myers, Michael P., Pass, Ian, Batty, Ian H., Van der Kaay, Jeroen, Stolarov, Javor P., Hemmings, Brian A., Wigler, Michael H., Downes, C. Peter, Tonks, Nicholas K.
Publicado em 1998

IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

Por Dixon, Miles J., Gray, Alexander, Schenning, Martijn, Agacan, Mark, Tempel, Wolfram, Tong, Yufeng, Nedyalkova, Lyudmila, Park, Hee-Won, Leslie, Nicholas R., van Aalten, Daan M. F., Downes, C. Peter, Batty, Ian H.
Publicado em 2012

Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Por McGuire, Victoria A., Gray, Alexander, Monk, Claire E., Santos, Susana G., Lee, Keunwook, Aubareda, Anna, Crowe, Jonathan, Ronkina, Natalia, Schwermann, Jessica, Batty, Ian H., Leslie, Nick R., Dean, Jonathan L. E., O'Keefe, Stephen J., Boothby, Mark, Gaestel, Matthias, Arthur, J. Simon C.
Publicado em 2013