Mechanistic Details of Glutathione Biosynthesis Revealed by Crystal Structures of Saccharomyces cerevisiae Glutamate Cysteine Ligase

Por Biterova, Ekaterina I., Barycki, Joseph J.
Publicado em 2009

Structural Basis for Feedback and Pharmacological Inhibition of Saccharomyces cerevisiae Glutamate Cysteine Ligase

Por Biterova, Ekaterina I., Barycki, Joseph J.
Publicado em 2010

Emerging roles for hyaluronidase in cancer metastasis and therapy

Por McAtee, Caitlin O., Barycki, Joseph J., Simpson, Melanie A.
Publicado no Adv Cancer Res (2014)

Emerging regulatory paradigms in glutathione metabolism

Por Liu, Yilin, Hyde, Annastasia S., Simpson, Melanie A., Barycki, Joseph J.
Publicado no Adv Cancer Res (2014)

UDP-glucose Dehydrogenase Activity and Optimal Downstream Cellular Function Require Dynamic Reorganization at the Dimer-Dimer Subunit Interfaces

Por Hyde, Annastasia S., Thelen, Ashley M., Barycki, Joseph J., Simpson, Melanie A.
Publicado em 2013

Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

Por Biterova, Ekaterina I., Turanov, Anton A., Gladyshev, Vadim N., Barycki, Joseph J.
Publicado em 2005

Crystal structure of acivicin-inhibited γ-glutamyltranspeptidase reveals critical roles for its C-terminus in autoprocessing and catalysis.

Por Williams, Kristin, Cullati, Sierra, Sand, Aaron, Biterova, Ekaterina I., Barycki, Joseph J.
Publicado em 2009

Hyaluronidase Activity of Human Hyal1 Requires Active Site Acidic and Tyrosine Residues

Por Zhang, Ling, Bharadwaj, Alamelu G., Casper, Andrew, Barkley, Joel, Barycki, Joseph J., Simpson, Melanie A.
Publicado em 2009

Inhibiting hexamer disassembly of human UDP-glucose dehydrogenase by photoactivated amino acid crosslinking

Por Grady, George, Thelen, Ashley, Albers, Jaleen, Ju, Tong, Guo, Jiantao, Barycki, Joseph J., Simpson, Melanie A.
Publicado no Biochemistry (2016)

Enzymatic defects underlying hereditary glutamate cysteine ligase deficiency are mitigated by association of the catalytic and regulatory subunits

Por Willis, Melanie Neely, Liu, Yilin, Biterova, Ekaterina I., Simpson, Melanie A., Kim, Heejeong, Lee, Jaekwon, Barycki, Joseph J.
Publicado em 2011

Cytosolic Fe-S Cluster Protein Maturation and Iron Regulation Are Independent of the Mitochondrial Erv1/Mia40 Import System

Por Ozer, Hatice K., Dlouhy, Adrienne C., Thornton, Jeremy D., Hu, Jingjing, Liu, Yilin, Barycki, Joseph J., Balk, Janneke, Outten, Caryn E.
Publicado no J Biol Chem (2015)

UDP-glucose Dehydrogenase Polymorphisms from Patients with Congenital Heart Valve Defects Disrupt Enzyme Stability and Quaternary Assembly

Por Hyde, Annastasia S., Farmer, Erin L., Easley, Katherine E., van Lammeren, Kristy, Christoffels, Vincent M., Barycki, Joseph J., Bakkers, Jeroen, Simpson, Melanie A.
Publicado em 2012

Potassium and the K(+)/H(+) Exchanger Kha1p Promote Binding of Copper to ApoFet3p Multi-copper Ferroxidase

Por Wu, Xiaobin, Kim, Heejeong, Seravalli, Javier, Barycki, Joseph J., Hart, P. John, Gohara, David W., Di Cera, Enrico, Jung, Won Hee, Kosman, Daniel J., Lee, Jaekwon
Publicado no J Biol Chem (2016)

Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential

Por Zimmer, Brenna M ., Howell, Michelle E., Wei, Qin, Ma, Linlin, Romsdahl, Trevor, Loughman, Eileen G., Markham, Jennifer E., Seravalli, Javier, Barycki, Joseph J., Simpson, Melanie A.
Publicado no Horm Cancer (2016)

5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for β-oxidation of fatty acids

Por Hanley, Peter J, Dröse, Stefan, Brandt, Ulrich, Lareau, Rachel A, Banerjee, Abir L, Srivastava, DK, Banaszak, Leonard J, Barycki, Joseph J, Van Veldhoven, Paul P, Daut, Jürgen
Publicado em 2005

Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking

Por McAtee, Caitlin O., Berkebile, Abigail R., Elowsky, Christian G., Fangman, Teresa, Barycki, Joseph J., Wahl, James K., Khalimonchuk, Oleh, Naslavsky, Naava, Caplan, Steve, Simpson, Melanie A.
Publicado no J Biol Chem (2015)