Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking

Hyaluronan (HA) turnover accelerates metastatic progression of prostate cancer in part by increasing rates of tumor cell proliferation and motility. To determine the mechanism, we overexpressed hyaluronidase 1 (Hyal1) as a fluorescent fusion protein and examined its impact on endocytosis and vesicul...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: McAtee, Caitlin O., Berkebile, Abigail R., Elowsky, Christian G., Fangman, Teresa, Barycki, Joseph J., Wahl, James K., Khalimonchuk, Oleh, Naslavsky, Naava, Caplan, Steve, Simpson, Melanie A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505569/
https://ncbi.nlm.nih.gov/pubmed/25855794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647446
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares