Hyaluronidase Hyal1 Increases Tumor Cell Proliferation and Motility through Accelerated Vesicle Trafficking

Hyaluronan (HA) turnover accelerates metastatic progression of prostate cancer in part by increasing rates of tumor cell proliferation and motility. To determine the mechanism, we overexpressed hyaluronidase 1 (Hyal1) as a fluorescent fusion protein and examined its impact on endocytosis and vesicul...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: McAtee, Caitlin O., Berkebile, Abigail R., Elowsky, Christian G., Fangman, Teresa, Barycki, Joseph J., Wahl, James K., Khalimonchuk, Oleh, Naslavsky, Naava, Caplan, Steve, Simpson, Melanie A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2015
Aiheet:
Glycobiology and Extracellular Matrices
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505569/
https://ncbi.nlm.nih.gov/pubmed/25855794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647446
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