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Two Novel Functions of Hyaluronidase-2 (Hyal2) Are Formation of the Glycocalyx and Control of CD44-ERM Interactions

It has long been predicted that the members of the hyaluronidase enzyme family have important non-enzymatic functions. However, their nature remains a mystery. The metabolism of hyaluronan (HA), their major enzymatic substrate, is also enigmatic. To examine the function of Hyal2, a glycosylphosphati...

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Hlavní autoři: Duterme, Cecile, Mertens-Strijthagen, Jeannine, Tammi, Markku, Flamion, Bruno
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785194/
https://ncbi.nlm.nih.gov/pubmed/19783662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044362
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