Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling

The hyaluronidase Hyal1 is clinically and functionally implicated in prostate cancer progression and metastasis. Elevated Hyal1 accelerates vesicular trafficking in prostate tumor cells, thereby enhancing their metastatic potential in an autocrine manner through increased motility and proliferation....

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Detalhes bibliográficos
Publicado no:Matrix Biol
Main Authors: McAtee, Caitlin O., Booth, Christine, Elowsky, Christian, Zhao, Lei, Payne, Jeremy, Fangman, Teresa, Caplan, Steve, Henry, Michael D., Simpson., Melanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230312/
https://ncbi.nlm.nih.gov/pubmed/29753676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2018.05.002
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