Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy

Por Ottolini, Matteo, Barker, Bryan S., Gaykema, Ronald P., Meisler, Miriam H., Patel, Manoj K.
Publicado no J Neurosci (2017)

The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin

Por Barker, Bryan S., Ottolini, Matteo, Wagnon, Jacy L., Hollander, Rachel, Meisler, Miriam H., Patel, Manoj K.
Publicado no Epilepsia (2016)

Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy

Por Barker, Bryan S., Nigam, Aradhya, Ottolini, Matteo, Gaykema, Ronald P., Hargus, Nicholas J., Patel, Manoj K.
Publicado no Neurobiol Dis (2017)

Loss-of-function variants of SCN8A in intellectual disability without seizures

Por Wagnon, Jacy L., Barker, Bryan S., Ottolini, Matteo, Park, Young, Volkheimer, Alicia, Valdez, Purnima, Swinkels, Marielle E.M., Patel, Manoj K., Meisler, Miriam H.
Publicado no Neurol Genet (2017)

Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy

Por Wagnon, Jacy L., Barker, Bryan S., Hounshell, James A., Haaxma, Charlotte A., Shealy, Amy, Moss, Timothy, Parikh, Sumit, Messer, Ricka D., Patel, Manoj K., Meisler, Miriam H.
Publicado no Ann Clin Transl Neurol (2015)

Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake

Por Warthen, Daniel M., Lambeth, Philip S., Ottolini, Matteo, Shi, Yingtang, Barker, Bryan Scot, Gaykema, Ronald P., Newmyer, Brandon A., Joy-Gaba, Jonathan, Ohmura, Yu, Perez-Reyes, Edward, Güler, Ali D., Patel, Manoj K., Scott, Michael M.
Publicado no Front Behav Neurosci (2016)

Genetically targeted magnetic control of the nervous system

Por Wheeler, Michael A., Smith, Cody J., Ottolini, Matteo, Barker, Bryan S., Purohit, Aarti M., Grippo, Ryan M., Gaykema, Ronald P., Spano, Anthony J., Beenhakker, Mark P., Kucenas, Sarah, Patel, Manoj K., Deppmann, Christopher D., Güler, Ali D.
Publicado no Nat Neurosci (2016)