Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy

Temporal lobe epilepsy (TLE) is a common form of adult epilepsy involving the limbic structures of the temporal lobe. Subiculum neurons act to provide a major output from the hippocampus and consist of a large population of endogenously bursting excitatory neurons. In TLE, subiculum neurons are larg...

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Bibliografiska uppgifter
I publikationen:Neurobiol Dis
Huvudupphovsmän: Barker, Bryan S., Nigam, Aradhya, Ottolini, Matteo, Gaykema, Ronald P., Hargus, Nicholas J., Patel, Manoj K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675750/
https://ncbi.nlm.nih.gov/pubmed/28860087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.08.018
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