Efficient Transient Transfection of Human Multiple Myeloma Cells by Electroporation – An Appraisal

door Steinbrunn, Torsten, Chatterjee, Manik, Bargou, Ralf C., Stühmer, Thorsten
Gepubliceerd in 2014

Silencing of CDK2, but not CDK1, separates mitogenic from anti-apoptotic signaling, sensitizing p53 defective cells for synthetic lethality

door Nekova, Tatyana S., Kneitz, Susanne, Einsele, Hermann, Bargou, Ralf, Stuhler, Gernot
Gepubliceerd in Cell Cycle (2016)

The IKK Inhibitor Bay 11-7082 Induces Cell Death Independent from Inhibition of Activation of NFκB Transcription Factors

door Rauert-Wunderlich, Hilka, Siegmund, Daniela, Maier, Eduard, Giner, Tina, Bargou, Ralf C., Wajant, Harald, Stühmer, Thorsten
Gepubliceerd in 2013

Loss of Serum and Glucocorticoid-Regulated Kinase 3 (SGK3) Does Not Affect Proliferation and Survival of Multiple Myeloma Cell Lines

door Hausmann, Stefan, Brandt, Evelyn, Köchel, Carolin, Einsele, Hermann, Bargou, Ralf C., Seggewiss-Bernhardt, Ruth, Stühmer, Thorsten
Gepubliceerd in PLoS One (2015)

Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

door Effenberger, Madlen, Bommert, Kathryn S., Kunz, Viktoria, Kruk, Jessica, Leich, Ellen, Rudelius, Martina, Bargou, Ralf, Bommert, Kurt
Gepubliceerd in Oncotarget (2017)

Targeting of the E3 ubiquitin-protein ligase HUWE1 impairs DNA repair capacity and tumor growth in preclinical multiple myeloma models

door Kunz, Viktoria, Bommert, Kathryn S., Kruk, Jessica, Schwinning, Daniel, Chatterjee, Manik, Stühmer, Thorsten, Bargou, Ralf, Bommert, Kurt
Gepubliceerd in Sci Rep (2020)

A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors

door Fink, Severin, Zugelder, Laurens, Roth, Bernhard, Brandt, Evelyn, Meloche, Sylvain, Izsvák, Zsuzsanna, Bargou, Ralf C., Stühmer, Thorsten
Gepubliceerd in PLoS One (2018)

Long-term outcome of patients with relapsed/refractory B-cell non-Hodgkin lymphoma treated with blinatumomab

door Dufner, Vera, Sayehli, Cyrus M., Chatterjee, Manik, Hummel, Horst D., Gelbrich, Götz, Bargou, Ralf C., Goebeler, Maria-Elisabeth
Gepubliceerd in Blood Adv (2019)

Assessment of TP53 lesions for p53 system functionality and drug resistance in multiple myeloma using an isogenic cell line model

door Munawar, Umair, Roth, Markus, Barrio, Santiago, Wajant, Harald, Siegmund, Daniela, Bargou, Ralf C., Kortüm, K. Martin, Stühmer, Thorsten
Gepubliceerd in Sci Rep (2019)

A systematic review of phase II trials of thalidomide/dexamethasone combination therapy in patients with relapsed or refractory multiple myeloma

door von Lilienfeld-Toal, Marie, Hahn-Ast, Corinna, Furkert, Kerstin, Hoffmann, Florian, Naumann, Ralph, Bargou, Ralf, Cook, Gordon, Glasmacher, Axel
Gepubliceerd in 2008

The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma

door Chatterjee, Manik, Andrulis, Mindaugas, Stühmer, Thorsten, Müller, Elisabeth, Hofmann, Claudia, Steinbrunn, Torsten, Heimberger, Tanja, Schraud, Heike, Kressmann, Stefanie, Einsele, Hermann, Bargou, Ralf C.
Gepubliceerd in 2013

Long‐term survival of patients with relapsed/refractory acute lymphoblastic leukemia treated with blinatumomab

door Topp, Max S., Gökbuget, Nicola, Zugmaier, Gerhard, Stein, Anthony S., Dombret, Hervé, Chen, Yuqi, Ribera, Josep‐Maria, Bargou, Ralf C., Horst, Heinz‐August, Kantarjian, Hagop M.
Gepubliceerd in Cancer (2020)

Subgroup-Independent Mapping of Renal Cell Carcinoma—Machine Learning Reveals Prognostic Mitochondrial Gene Signature Beyond Histopathologic Boundaries

door Marquardt, André, Solimando, Antonio Giovanni, Kerscher, Alexander, Bittrich, Max, Kalogirou, Charis, Kübler, Hubert, Rosenwald, Andreas, Bargou, Ralf, Kollmannsberger, Philip, Schilling, Bastian, Meierjohann, Svenja, Krebs, Markus
Gepubliceerd in Front Oncol (2021)

Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma

door Keppler, Sarah, Weiβbach, Susann, Langer, Christian, Knop, Stefan, Pischimarov, Jordan, Kull, Miriam, Stühmer, Thorsten, Steinbrunn, Torsten, Bargou, Ralf, Einsele, Hermann, Rosenwald, Andreas, Leich, Ellen
Gepubliceerd in Oncotarget (2016)

miR-221-3p Regulates VEGFR2 Expression in High-Risk Prostate Cancer and Represents an Escape Mechanism from Sunitinib In Vitro

door Krebs, Markus, Solimando, Antonio Giovanni, Kalogirou, Charis, Marquardt, André, Frank, Torsten, Sokolakis, Ioannis, Hatzichristodoulou, Georgios, Kneitz, Susanne, Bargou, Ralf, Kübler, Hubert, Schilling, Bastian, Spahn, Martin, Kneitz, Burkhard
Gepubliceerd in J Clin Med (2020)

Specific Detection of CD56 (NCAM) Isoforms for the Identification of Aggressive Malignant Neoplasms with Progressive Development

door Gattenlöhner, Stefan, Stühmer, Thorsten, Leich, Ellen, Reinhard, Matthias, Etschmann, Benjamin, Völker, Hans-Ulrich, Rosenwald, Andreas, Serfling, Edgar, Christian Bargou, Ralf, Ertl, Georg, Einsele, Hermann, Müller-Hermelink, Hans-Konrad
Gepubliceerd in 2009

Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapsed/refractory diffuse large B-cell lymphoma

door Viardot, Andreas, Goebeler, Marie-Elisabeth, Hess, Georg, Neumann, Svenja, Pfreundschuh, Michael, Adrian, Nicole, Zettl, Florian, Libicher, Martin, Sayehli, Cyrus, Stieglmaier, Julia, Zhang, Alicia, Nagorsen, Dirk, Bargou, Ralf C.
Gepubliceerd in Blood (2016)

Long-term relapse-free survival in a phase 2 study of blinatumomab for the treatment of patients with minimal residual disease in B-lineage acute lymphoblastic leukemia

door Gökbuget, Nicola, Zugmaier, Gerhard, Klinger, Matthias, Kufer, Peter, Stelljes, Matthias, Viardot, Andreas, Horst, Heinz A., Neumann, Svenja, Brüggemann, Monika, Ottmann, Oliver G., Burmeister, Thomas, Wessiepe, Dorothea, Topp, Max S., Bargou, Ralf
Gepubliceerd in Haematologica (2017)

Proof of concept for a rapidly switchable universal CAR-T platform with UniCAR-T-CD123 in relapsed/refractory AML

door Wermke, Martin, Kraus, Sabrina, Ehninger, Armin, Bargou, Ralf C., Goebeler, Maria-Elisabeth, Middeke, Jan Moritz, Kreissig, Carla, von Bonin, Malte, Koedam, Jan, Pehl, Michael, Bornhäuser, Martin, Einsele, Hermann, Ehninger, Gerhard, Cartellieri, Marc
Gepubliceerd in Blood (2021)

Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma

door Leich, Ellen, Schreder, Martin, Pischimarov, Jordan, Stühmer, Thorsten, Steinbrunn, Torsten, Rudelius, Martina, Brünnert, Daniela, Chatterjee, Manik, Langer, Christian, Keppler, Sarah, Heredia-Guerrero, Sofia Catalina, Einsele, Hermann, Knop, Stefan, Bargou, Ralf Christian, Rosenwald, Andreas
Gepubliceerd in Blood Cancer J (2021)