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Glutaminase inhibition in multiple myeloma induces apoptosis via MYC degradation

Multiple Myeloma (MM) is an incurable hematological malignancy affecting millions of people worldwide. As in all tumor cells both glucose and more recently glutamine have been identified as important for MM cellular metabolism, however there is some dispute as to the role of glutamine in MM cell sur...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Effenberger, Madlen, Bommert, Kathryn S., Kunz, Viktoria, Kruk, Jessica, Leich, Ellen, Rudelius, Martina, Bargou, Ralf, Bommert, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5689652/
https://ncbi.nlm.nih.gov/pubmed/29156762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20691
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