The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival

Y-box binding protein 1 (YB-1) functions as a translational regulator and has been suggested to elevate MYC mRNA translation via an internal ribosome entry segment (IRES) point mutation in multiple myeloma (MM). We show that YB-1-mediated translation of MYC mRNA occurs independently of the reported...

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Detalhes bibliográficos
Main Authors: Bommert, KS, Effenberger, M, Leich, E, Küspert, M, Murphy, D, Langer, C, Moll, R, Janz, S, Mottok, A, Weissbach, S, Rosenwald, A, Bargou, R, Bommert, K
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047128/
https://ncbi.nlm.nih.gov/pubmed/22772059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.185
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