miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth

Deregulated microRNA (miR)/transcription factor (TF)-based networks represent a hallmark of cancer. We report here a novel c-Myc/miR-23b/Sp1 feed-forward loop with a critical role in multiple myeloma (MM) and Waldenstrom's macroglobulinemia (WM) cell growth and survival. We have found miR-23b t...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Fulciniti, M, Amodio, N, Bandi, R L, Cagnetta, A, Samur, M K, Acharya, C, Prabhala, R, D'Aquila, P, Bellizzi, D, Passarino, G, Adamia, S, Neri, A, Hunter, Z R, Treon, S P, Anderson, K C, Tassone, P, Munshi, N C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742623/
https://ncbi.nlm.nih.gov/pubmed/26771806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.106
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