miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells

Epigenetic silencing of tumor suppressor genes frequently occurs and may account for their inactivation in cancer cells. We previously demonstrated that miR-29b is a tumor suppressor microRNA (miRNA) that targets de novo DNA methyltransferases and reduces the global DNA methylation of multiple myelo...

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Main Authors: Amodio, Nicola, Bellizzi, Dina, Leotta, Marzia, Raimondi, Lavinia, Biamonte, Lavinia, D’Aquila, Patrizia, Di Martino, Maria Teresa, Calimeri, Teresa, Rossi, Marco, Lionetti, Marta, Leone, Emanuela, Passarino, Giuseppe, Neri, Antonino, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903716/
https://ncbi.nlm.nih.gov/pubmed/24091729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26585
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