miR-29b induces SOCS-1 expression by promoter demethylation and negatively regulates migration of multiple myeloma and endothelial cells

Epigenetic silencing of tumor suppressor genes frequently occurs and may account for their inactivation in cancer cells. We previously demonstrated that miR-29b is a tumor suppressor microRNA (miRNA) that targets de novo DNA methyltransferases and reduces the global DNA methylation of multiple myelo...

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Detalhes bibliográficos
Main Authors: Amodio, Nicola, Bellizzi, Dina, Leotta, Marzia, Raimondi, Lavinia, Biamonte, Lavinia, D’Aquila, Patrizia, Di Martino, Maria Teresa, Calimeri, Teresa, Rossi, Marco, Lionetti, Marta, Leone, Emanuela, Passarino, Giuseppe, Neri, Antonino, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903716/
https://ncbi.nlm.nih.gov/pubmed/24091729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26585
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