DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma

Aberrant DNA methylation plays a relevant role in multiple myeloma (MM) pathogenesis. MicroRNAs (miRNAs) are a class of small non-coding RNAs that recently emerged as master regulator of gene expression by targeting protein-coding mRNAs. However, miRNAs involvement in the regulation of the epigeneti...

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Bibliografische gegevens
Hoofdauteurs: Amodio, Nicola, Leotta, Marzia, Bellizzi, Dina, Di Martino, Maria Teresa, D'Aquila, Patrizia, Lionetti, Marta, Fabiani, Fernanda, Leone, Emanuela, Gullà, Anna Maria, Passarino, Giuseppe, Caraglia, Michele, Negrini, Massimo, Neri, Antonino, Giordano, Antonio, Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2012
Onderwerpen:
Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717964/
https://ncbi.nlm.nih.gov/pubmed/23100393
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