Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth

PURPOSE: Deregulated expression of microRNAs (miRNAs) plays a role in the pathogenesis and progression of multiple myeloma (MM). Among upregulated miRNAs, miR-21 has oncogenic potential and therefore represents an attractive target for the treatment of MM. EXPERIMENTAL DESIGN: Here, we investigated...

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Bibliografski detalji
Glavni autori: Leone, Emanuela, Morelli, Eugenio, Di Martino, Maria T., Amodio, Nicola, Foresta, Umberto, Gullà, Annamaria, Rossi, Marco, Neri, Antonino, Giordano, Antonio, Munshi, Nikhil C., Anderson, Kenneth C., Tagliaferri, Pierosandro, Tassone, Pierfrancesco
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147955/
https://ncbi.nlm.nih.gov/pubmed/23446999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3325
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