Subgroup-Independent Mapping of Renal Cell Carcinoma—Machine Learning Reveals Prognostic Mitochondrial Gene Signature Beyond Histopathologic Boundaries

Background: Renal cell carcinoma (RCC) is divided into three major histopathologic groups—clear cell (ccRCC), papillary (pRCC) and chromophobe RCC (chRCC). We performed a comprehensive re-analysis of publicly available RCC datasets from the TCGA (The Cancer Genome Atlas) database, thereby combining...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Marquardt, André, Solimando, Antonio Giovanni, Kerscher, Alexander, Bittrich, Max, Kalogirou, Charis, Kübler, Hubert, Rosenwald, Andreas, Bargou, Ralf, Kollmannsberger, Philip, Schilling, Bastian, Meierjohann, Svenja, Krebs, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005734/
https://ncbi.nlm.nih.gov/pubmed/33791209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.621278
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