CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo

door Aryal, Neeraj K, Wasylishen, Amanda R, Lozano, Guillermina
Gepubliceerd in Cell Death Dis (2018)

Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53

door Aryal, Neeraj K., Wasylishen, Amanda R., Pant, Vinod, Riley-Croce, Maurisa, Lozano, Guillermina
Gepubliceerd in Oncotarget (2017)

The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumorigenesis

door Xiong, Shunbin, Pant, Vinod, Zhang, Yun, Aryal, Neeraj K, You, M. James, Kusewitt, Donna, Lozano, Guillermina
Gepubliceerd in J Pathol (2017)

Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

door Pant, Vinod, Xiong, Shunbin, Wasylishen, Amanda R., Larsson, Connie A., Aryal, Neeraj K., Chau, Gilda, Tailor, Ramesh C., Lozano, Guillermina
Gepubliceerd in Proc Natl Acad Sci U S A (2019)

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo

door Aryal, Neeraj K., Pant, Vinod, Wasylishen, Amanda R., Parker-Thornburg, Jan, Baseler, Laura, El-Naggar, Adel K., Liu, Bin, Kalia, Awdhesh, Lozano, Guillermina, Arur, Swathi
Gepubliceerd in Proc Natl Acad Sci U S A (2019)

Dicer1 phospho-mimetic promotes tumor progression and dissemination

door Aryal, Neeraj K, Pant, Vinod, Wasylishen, Amanda R., Rimel, Bobbie, Baseler, Laura, El-Naggar, Adel K., Mutch, David G., Goodfellow, Paul J, Arur, Swathi, Lozano, Guillermina
Gepubliceerd in Cancer Res (2019)

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo

door Wasylishen, Amanda R., Sun, Chang, Moyer, Sydney M., Qi, Yuan, Chau, Gilda P., Aryal, Neeraj K., McAllister, Florencia, Kim, Michael P., Barton, Michelle C., Estrella, Jeannelyn S., Su, Xiaoping, Lozano, Guillermina
Gepubliceerd in Sci Adv (2020)