CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo

Por Aryal, Neeraj K, Wasylishen, Amanda R, Lozano, Guillermina
Publicado no Cell Death Dis (2018)

Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53

Por Aryal, Neeraj K., Wasylishen, Amanda R., Pant, Vinod, Riley-Croce, Maurisa, Lozano, Guillermina
Publicado no Oncotarget (2017)

The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumorigenesis

Por Xiong, Shunbin, Pant, Vinod, Zhang, Yun, Aryal, Neeraj K, You, M. James, Kusewitt, Donna, Lozano, Guillermina
Publicado no J Pathol (2017)

Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

Por Pant, Vinod, Xiong, Shunbin, Wasylishen, Amanda R., Larsson, Connie A., Aryal, Neeraj K., Chau, Gilda, Tailor, Ramesh C., Lozano, Guillermina
Publicado no Proc Natl Acad Sci U S A (2019)

Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo

Por Aryal, Neeraj K., Pant, Vinod, Wasylishen, Amanda R., Parker-Thornburg, Jan, Baseler, Laura, El-Naggar, Adel K., Liu, Bin, Kalia, Awdhesh, Lozano, Guillermina, Arur, Swathi
Publicado no Proc Natl Acad Sci U S A (2019)

Dicer1 phospho-mimetic promotes tumor progression and dissemination

Por Aryal, Neeraj K, Pant, Vinod, Wasylishen, Amanda R., Rimel, Bobbie, Baseler, Laura, El-Naggar, Adel K., Mutch, David G., Goodfellow, Paul J, Arur, Swathi, Lozano, Guillermina
Publicado no Cancer Res (2019)

Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo

Por Wasylishen, Amanda R., Sun, Chang, Moyer, Sydney M., Qi, Yuan, Chau, Gilda P., Aryal, Neeraj K., McAllister, Florencia, Kim, Michael P., Barton, Michelle C., Estrella, Jeannelyn S., Su, Xiaoping, Lozano, Guillermina
Publicado no Sci Adv (2020)