Pharmacological approaches to restore mitochondrial function

Por Andreux, Pénélope A., Houtkooper, Riekelt H., Auwerx, Johan
Publicado em 2013

Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19)

Por Singh, Anurag, Andreux, Pénélope, Blanco, William, Auwerx, Johan, Rinsch, Chris
Publicado no Curr Dev Nutr (2019)

Bioavailable copper modulates oxidative phosphorylation and growth of tumors

Por Ishida, Seiko, Andreux, Pénélope, Poitry-Yamate, Carole, Auwerx, Johan, Hanahan, Douglas
Publicado em 2013

An Evolutionarily Conserved Role for the Aryl Hydrocarbon Receptor in the Regulation of Movement

Por Williams, Evan G., Mouchiroud, Laurent, Frochaux, Michael, Pandey, Ashutosh, Andreux, Pénélope A., Deplancke, Bart, Auwerx, Johan
Publicado em 2014

Autophagy Defect Is Associated with Low Glucose-Induced Apoptosis in 661W Photoreceptor Cells

Por Balmer, Delphine, Emery, Martine, Andreux, Pénélope, Auwerx, Johan, Ginet, Vanessa, Puyal, Julien, Schorderet, Daniel F., Roduit, Raphaël
Publicado em 2013

Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis

Por Lim, Maria A., Bence, Kendra K., Sandesara, Ishani, Andreux, Pénélope, Auwerx, Johan, Ishibashi, Jeff, Seale, Patrick, Kalb, Robert G.
Publicado em 2014

A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans

Por Andreux, Pénélope A., Mouchiroud, Laurent, Wang, Xu, Jovaisaite, Virginija, Mottis, Adrienne, Bichet, Sabrina, Moullan, Norman, Houtkooper, Riekelt H., Auwerx, Johan
Publicado em 2014

Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly

Por Andreux, Pénélope A., van Diemen, Marcus P. J., Heezen, Maxime R., Auwerx, Johan, Rinsch, Chris, Groeneveld, Geert Jan, Singh, Anurag
Publicado no Sci Rep (2018)

Publisher Correction: Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly

Por Andreux, Pénélope A., van Diemen, Marcus P. J., Heezen, Maxime R., Auwerx, Johan, Rinsch, Chris, Groeneveld, Geert Jan, Singh, Anurag
Publicado no Sci Rep (2019)

An unbiased silencing screen in muscle cells identifies miR-320a, miR-150, miR-196b, and miR-34c as regulators of skeletal muscle mitochondrial metabolism

Por Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Jörgensen, Johanna A., Wang, Xu, de Windt, Leon J., Schrauwen, Patrick, Auwerx, Johan, Hoeks, Joris
Publicado no Mol Metab (2017)

MicroRNA‐382 silencing induces a mitonuclear protein imbalance and activates the mitochondrial unfolded protein response in muscle cells

Por Dahlmans, Dennis, Houzelle, Alexandre, Andreux, Pénélope, Wang, Xu, Jörgensen, Johanna A., Moullan, Norman, Daemen, Sabine, Kersten, Sander, Auwerx, Johan, Hoeks, Joris
Publicado no J Cell Physiol (2018)

Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits

Por Andreux, Pénélope A., Williams, Evan G., Koutnikova, Hana, Houtkooper, Riekelt H., Champy, Marie-France, Henry, Hugues, Schoonjans, Kristina, Williams, Robert W., Auwerx, Johan
Publicado em 2012

The metabolic footprint of aging in mice

Por Houtkooper, Riekelt H., Argmann, Carmen, Houten, Sander M., Cantó, Carles, Jeninga, Ellen H., Andreux, Pénélope A., Thomas, Charles, Doenlen, Raphaël, Schoonjans, Kristina, Auwerx, Johan
Publicado em 2011

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial proteins without affecting global metabolic homeostasis

Por Fernandez-Marcos, Pablo J., Jeninga, Ellen H., Canto, Carles, Harach, Taoufiq, de Boer, Vincent C. J., Andreux, Penelope, Moullan, Norman, Pirinen, Eija, Yamamoto, Hiroyasu, Houten, Sander M., Schoonjans, Kristina, Auwerx, Johan
Publicado em 2012

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity

Por Cantó, Carles, Houtkooper, Riekelt H., Pirinen, Eija, Youn, Dou Y., Oosterveer, Maaike H., Cen, Yana, Fernandez-Marcos, Pablo J., Yamamoto, Hiroyasu, Andreux, Pénélope A., Cettour-Rose, Philippe, Gademann, Karl, Rinsch, Chris, Schoonjans, Kristina, Sauve, Anthony A., Auwerx, Johan
Publicado em 2012

Murine Gut Microbiota Is Defined by Host Genetics and Modulates Variation of Metabolic Traits

Por McKnite, Autumn M., Perez-Munoz, Maria Elisa, Lu, Lu, Williams, Evan G., Brewer, Simon, Andreux, Pénélope A., Bastiaansen, John W. M., Wang, Xusheng, Kachman, Stephen D., Auwerx, Johan, Williams, Robert W., Benson, Andrew K., Peterson, Daniel A., Ciobanu, Daniel C.
Publicado em 2012

ARDD 2020: from aging mechanisms to interventions

Por Mkrtchyan, Garik V., Abdelmohsen, Kotb, Andreux, Pénélope, Bagdonaite, Ieva, Barzilai, Nir, Brunak, Søren, Cabreiro, Filipe, de Cabo, Rafael, Campisi, Judith, Cuervo, Ana Maria, Demaria, Marco, Ewald, Collin Y., Fang, Evandro Fei, Faragher, Richard, Ferrucci, Luigi, Freund, Adam, Silva-García, Carlos G., Georgievskaya, Anastasia, Gladyshev, Vadim N., Glass, David J., Gorbunova, Vera, de Grey, Aubrey, He, Wei-Wu, Hoeijmakers, Jan, Hoffmann, Eva, Horvath, Steve, Houtkooper, Riekelt H., Jensen, Majken K., Jensen, Martin Borch, Kane, Alice, Kassem, Moustapha, de Keizer, Peter, Kennedy, Brian, Karsenty, Gerard, Lamming, Dudley W., Lee, Kai-Fu, MacAulay, Nanna, Mamoshina, Polina, Mellon, Jim, Molenaars, Marte, Moskalev, Alexey, Mund, Andreas, Niedernhofer, Laura, Osborne, Brenna, Pak, Heidi H., Parkhitko, Andrey, Raimundo, Nuno, Rando, Thomas A., Rasmussen, Lene Juel, Reis, Carolina, Riedel, Christian G., Franco-Romero, Anais, Schumacher, Björn, Sinclair, David A., Suh, Yousin, Taub, Pam R., Toiber, Debra, Treebak, Jonas T., Valenzano, Dario Riccardo, Verdin, Eric, Vijg, Jan, Young, Sergey, Zhang, Lei, Bakula, Daniela, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Publicado no Aging (Albany NY) (2020)