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A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans

Mitochondria are semi-autonomous organelles regulated by a complex network of proteins that are vital for many cellular functions. Because mitochondrial modulators can impact many aspects of cellular homeostasis, their identification and validation has proven challenging. It requires the measurement...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Andreux, Pénélope A., Mouchiroud, Laurent, Wang, Xu, Jovaisaite, Virginija, Mottis, Adrienne, Bichet, Sabrina, Moullan, Norman, Houtkooper, Riekelt H., Auwerx, Johan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055904/
https://ncbi.nlm.nih.gov/pubmed/24923838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05285
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