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The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

The ability to respond to various intracellular and/or extracellular stresses allows the organism to adapt to changing environmental conditions and drives evolution. It is now well accepted that a progressive decline of the efficiency of stress response pathways occurs with aging. In this context, a...

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Autores principales: Jovaisaite, Virginija, Mouchiroud, Laurent, Auwerx, Johan
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867496/
https://ncbi.nlm.nih.gov/pubmed/24353213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jeb.090738
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