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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of organisms. Mitochondrial dysfunction activates an unfolded protein response (UPR(mt)), a stress signaling mechanism designed to ensure mitochondrial homeostasis. Perturbation of mitochondria during la...
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Publicado no: | Cell |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889222/ https://ncbi.nlm.nih.gov/pubmed/27133168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.012 |
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