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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
Across eukaryotic species, mild mitochondrial stress can have beneficial effects on the lifespan of organisms. Mitochondrial dysfunction activates an unfolded protein response (UPR(mt)), a stress signaling mechanism designed to ensure mitochondrial homeostasis. Perturbation of mitochondria during la...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889222/ https://ncbi.nlm.nih.gov/pubmed/27133168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.012 |
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