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A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans
Mitochondria are semi-autonomous organelles regulated by a complex network of proteins that are vital for many cellular functions. Because mitochondrial modulators can impact many aspects of cellular homeostasis, their identification and validation has proven challenging. It requires the measurement...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055904/ https://ncbi.nlm.nih.gov/pubmed/24923838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05285 |
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