Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation

par Alquezar, Carolina, Arya, Shruti, Kao, Aimee W.
Publié dans Front Neurol (2021)

Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers

par Alquézar, Carolina, de la Encarnación, Ana, Moreno, Fermín, de Munain, Adolfo López, Martín-Requero, Ángeles
Publié dans J Psychiatry Neurosci (2016)

Calmodulin levels in blood cells as a potential biomarker of Alzheimer’s disease

par Esteras, Noemí, Alquézar, Carolina, de la Encarnación, Ana, Villarejo, Alberto, Bermejo-Pareja, Félix, Martín-Requero, Ángeles
Publié 2013

Inactivation of CDK/pRb Pathway Normalizes Survival Pattern of Lymphoblasts Expressing the FTLD-Progranulin Mutation c.709-1G>A

par Alquezar, Carolina, Esteras, Noemí, Alzualde, Ainhoa, Moreno, Fermín, Ayuso, Matilde S., López de Munain, Adolfo, Martín-Requero, Ángeles
Publié 2012

Familial Alzheimer’s Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants

par Wojsiat, Joanna, Laskowska-Kaszub, Katarzyna, Alquézar, Carolina, Białopiotrowicz, Emilia, Esteras, Noemi, Zdioruk, Mykola, Martin-Requero, Angeles, Wojda, Urszula
Publié dans Mol Neurobiol (2016)

Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease Patients

par Cosín-Tomàs, Marta, Senserrich, Júlia, Arumí-Planas, Marta, Alquézar, Carolina, Pallàs, Mercè, Martín-Requero, Ángeles, Suñol, Cristina, Kaliman, Perla, Sanfeliu, Coral
Publié dans Nutrients (2019)

Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons

par Alquezar, Carolina, Felix, Jessica B., McCandlish, Elizabeth, Buckley, Brian T., Caparros-Lefebvre, Dominique, Karch, Celeste M., Golbe, Lawrence I., Kao, Aimee W.
Publié dans Sci Rep (2020)

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia

par Alquezar, Carolina, Salado, Irene G., de la Encarnación, Ana, Pérez, Daniel I., Moreno, Fermín, Gil, Carmen, de Munain, Adolfo López, Martínez, Ana, Martín-Requero, Ángeles
Publié dans Mol Neurodegener (2016)

Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH

par Chin, Marcus Y., Patwardhan, Anand R., Ang, Kean-Hooi, Wang, Austin L., Alquezar, Carolina, Welch, Mackenzie, Nguyen, Phi T., Grabe, Michael, Molofsky, Anna V., Arkin, Michelle R., Kao, Aimee W.
Publié dans ACS Sens (2021)

Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia

par Olney, Nicholas T., Alquezar, Carolina, Ramos, Eliana Marisa, Nana, Alissa L., Fong, Jamie C., Karydas, Anna M., Taylor, Joanne B., Stephens, Melanie L., Argouarch, Andrea R., Van Berlo, Victoria A., Dokuru, Deepika R., Sherr, Elliott H., Jicha, Gregory A., Dillon, William P., Desikan, Rahul S., De May, Mary, Seeley, William W., Coppola, Giovanni, Miller, Bruce L., Kao, Aimee W.
Publié dans Acta Neuropathol (2017)