Inhibition of Pneumocystis carinii dihydropteroate synthetase by para-acetamidobenzoic acid: possible mechanism of action of isoprinosine in human immunodeficiency virus infection.

Por Kovacs, J A, Powell, F, Voeller, D, Allegra, C J
Publicado em 1993

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Por Allegra, C J, Drake, J C, Jolivet, J, Chabner, B A
Publicado em 1985

Effect of methotrexate on intracellular folate pools in purified myeloid precursor cells from normal human bone marrow.

Por Baram, J, Allegra, C J, Fine, R L, Chabner, B A
Publicado em 1987

The effect of dose and interval between 5-fluorouracil and leucovorin on the formation of thymidylate synthase ternary complex in human cancer cells.

Por Drake, J. C., Voeller, D. M., Allegra, C. J., Johnston, P. G.
Publicado em 1995

Identification of in vivo target RNA sequences bound by thymidylate synthase.

Por Chu, E, Cogliati, T, Copur, S M, Borre, A, Voeller, D M, Allegra, C J, Segal, S
Publicado em 1996

Determinants of trimetrexate lethality in human colon cancer cells.

Por Grem, J. L., Voeller, D. M., Geoffroy, F., Horak, E., Johnston, P. G., Allegra, C. J.
Publicado em 1994

Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.

Por Allegra, C J, Boarman, D, Kovacs, J A, Morrison, P, Beaver, J, Chabner, B A, Masur, H
Publicado em 1990

Potent in vitro and in vivo antitoxoplasma activity of the lipid-soluble antifolate trimetrexate.

Por Allegra, C J, Kovacs, J A, Drake, J C, Swan, J C, Chabner, B A, Masur, H
Publicado em 1987

Identification of a thymidylate synthase ribonucleoprotein complex in human colon cancer cells.

Por Chu, E, Voeller, D M, Jones, K L, Takechi, T, Maley, G F, Maley, F, Segal, S, Allegra, C J
Publicado em 1994

Potent antipneumocystis and antitoxoplasma activities of piritrexim, a lipid-soluble antifolate.

Por Kovacs, J A, Allegra, C J, Swan, J C, Drake, J C, Parrillo, J E, Chabner, B A, Masur, H
Publicado em 1988

Thymidylate synthase binds to c-myc RNA in human colon cancer cells and in vitro.

Por Chu, E, Takechi, T, Jones, K L, Voeller, D M, Copur, S M, Maley, G F, Maley, F, Segal, S, Allegra, C J
Publicado em 1995

Polyglutamation of methotrexate. Is methotrexate a prodrug?

Por Chabner, B A, Allegra, C J, Curt, G A, Clendeninn, N J, Baram, J, Koizumi, S, Drake, J C, Jolivet, J
Publicado em 1985

Identification of an RNA binding site for human thymidylate synthase.

Por Chu, E, Voeller, D, Koeller, D M, Drake, J C, Takimoto, C H, Maley, G F, Maley, F, Allegra, C J
Publicado em 1993

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.

Por Chu, E, Koeller, D M, Casey, J L, Drake, J C, Chabner, B A, Elwood, P C, Zinn, S, Allegra, C J
Publicado em 1991

Mechanism of pyrimethamine resistance in recent isolates of Plasmodium falciparum.

Por McCutchan, T F, Welsh, J A, Dame, J B, Quakyi, I A, Graves, P M, Drake, J C, Allegra, C J
Publicado em 1984

Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells.

Por Pestalozzi, B. C., McGinn, C. J., Kinsella, T. J., Drake, J. C., Glennon, M. C., Allegra, C. J., Johnston, P. G.
Publicado em 1995

Characterization of a specific interaction between Escherichia coli thymidylate synthase and Escherichia coli thymidylate synthase mRNA.

Por Voeller, D M, Changchien, L M, Maley, G F, Maley, F, Takechi, T, Turner, R E, Montfort, W R, Allegra, C J, Chu, E
Publicado em 1995

Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients

Por Paradiso, A, Simone, G, Petroni, S, Leone, B, Vallejo, C, Lacava, J, Romero, A, Machiavelli, M, Lena, M De, Allegra, C J, Johnston, P G
Publicado em 2000

Bioavailability of oral trimetrexate in patients with acquired immunodeficiency syndrome.

Por Rogers, P, Allegra, C J, Murphy, R F, Drake, J C, Masur, H, Poplack, D G, Chabner, B A, Parrillo, J E, Lane, H C, Balis, F M
Publicado em 1988