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Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.

Toxoplasma gondii is a common protozoan disease that often causes life-threatening disease, particularly among patients with the acquired immunodeficiency syndrome. This study demonstrates that the dihydropteroate synthase in T. gondii is kinetically distinct from the enzyme characterized from other...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Allegra, C J, Boarman, D, Kovacs, J A, Morrison, P, Beaver, J, Chabner, B A, Masur, H
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114448
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