Primary structure and expression of the dihydropteroate synthetase gene of Plasmodium falciparum.
The enzyme dihydropteroate synthetase (DHPS) from Plasmodium falciparum is involved in the mechanism of action of the sulfone/sulfonamide group of drugs. We describe the cloning and sequencing of the gene encoding the P. falciparum DHPS enzyme and show that it is a bifunctional enzyme that includes...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44356/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8041761/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.15.7149 |
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