Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase.

Toxoplasma gondii is a common protozoan disease that often causes life-threatening disease, particularly among patients with the acquired immunodeficiency syndrome. This study demonstrates that the dihydropteroate synthase in T. gondii is kinetically distinct from the enzyme characterized from other...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Allegra, C J, Boarman, D, Kovacs, J A, Morrison, P, Beaver, J, Chabner, B A, Masur, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2298911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114448
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