Human genetics of infectious diseases: between proof of principle and paradigm

di Alcaïs, Alexandre, Abel, Laurent, Casanova, Jean-Laurent
Pubblicazione 2009

Tuberculosis in children and adults: two distinct genetic diseases

di Alcaïs, Alexandre, Fieschi, Claire, Abel, Laurent, Casanova, Jean-Laurent
Pubblicazione 2005

Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

di Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Pubblicazione 2005

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction

di Fava, Vinicius M., Sales-Marques, Carolinne, Alcaïs, Alexandre, Moraes, Milton O., Schurr, Erwin
Pubblicato in Front Immunol (2017)

Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes

di Fava, Vinicius M., Cobat, Aurélie, Gzara, Chaïma, Alcaïs, Alexandre, Abel, Laurent, Schurr, Erwin
Pubblicato in Proc Natl Acad Sci U S A (2020)

Evaluation of Approaches to Identify Associated SNPs That Explain the Linkage Evidence in Nuclear Families with Affected Siblings

di Chen, Ming-Huei, Van Eerdewegh, Paul, Vincent, Quentin B., Alcais, Alexandre, Abel, Laurent, Dupuis, Josée
Pubblicazione 2010

Highly Significant Association between Two Common Single Nucleotide Polymorphisms in CORIN Gene and Preeclampsia in Caucasian Women

di Stepanian, Alain, Alcaïs, Alexandre, de Prost, Dominique, Tsatsaris, Vassilis, Dreyfus, Michel, Treluyer, Jean-Marc, Mandelbrot, Laurent
Pubblicato in PLoS One (2014)

Tuberculin Skin Test Reactivity Is Dependent on Host Genetic Background in Colombian Tuberculosis Household Contacts

di Cobat, Aurélie, Barrera, Luis F., Henao, Hanna, Arbeláez, Patricia, Abel, Laurent, García, Luis F., Schurr, Erwin, Alcaïs, Alexandre
Pubblicazione 2012

Somatic Hypermutation at A/T-Rich Oligonucleotide Substrates Shows Different Strand Polarities in Ung-Deficient or -Proficient Backgrounds

di Zivojnovic, Marija, Delbos, Frédéric, Girelli Zubani, Giulia, Julé, Amélie, Alcais, Alexandre, Weill, Jean-Claude, Reynaud, Claude-Agnès, Storck, Sébastien
Pubblicazione 2014

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy

di Fava, Vinicius M., Manry, Jérémy, Cobat, Aurélie, Orlova, Marianna, Van Thuc, Nguyen, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Pubblicato in PLoS Negl Trop Dis (2016)

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

di Dallmann-Sauer, Monica, Fava, Vinicius M., Gzara, Chaïma, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Schurr, Erwin
Pubblicato in PLoS Pathog (2020)

Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

di Manry, Jeremy, Vincent, Quentin B., Johnson, Christian, Chrabieh, Maya, Lorenzo, Lazaro, Theodorou, Ioannis, Ardant, Marie-Françoise, Marion, Estelle, Chauty, Annick, Marsollier, Laurent, Abel, Laurent, Alcaïs, Alexandre
Pubblicato in Commun Biol (2020)

Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases

di Gaschignard, Jean, Grant, Audrey Virginia, Thuc, Nguyen Van, Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Schurr, Erwin, Alcaïs, Alexandre
Pubblicato in PLoS Negl Trop Dis (2016)

Gene Set Signature of Reversal Reaction Type I in Leprosy Patients

di Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Pubblicazione 2013

Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

di Belkadi, Aziz, Pedergnana, Vincent, Cobat, Aurélie, Itan, Yuval, Vincent, Quentin B., Abhyankar, Avinash, Shang, Lei, El Baghdadi, Jamila, Bousfiha, Aziz, Alcais, Alexandre, Boisson, Bertrand, Casanova, Jean-Laurent, Abel, Laurent
Pubblicato in Proc Natl Acad Sci U S A (2016)

Family-based genome-wide association study of leprosy in Vietnam

di Gzara, Chaima, Dallmann-Sauer, Monica, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Fava, Vinicius M., Bihoreau, Marie-Thérèse, Boland, Anne, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin, Cobat, Aurélie
Pubblicato in PLoS Pathog (2020)

PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages

di de Léséleuc, Louis, Orlova, Marianna, Cobat, Aurelie, Girard, Manon, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Truman, Richard, Spencer, John S., Adams, Linda, Thai, Vu Hong, Alcais, Alexandre, Schurr, Erwin
Pubblicazione 2013

Combined Linkage and Association Studies Show that HLA Class II Variants Control Levels of Antibodies against Epstein-Barr Virus Antigens

di Pedergnana, Vincent, Syx, Laurène, Cobat, Aurélie, Guergnon, Julien, Brice, Pauline, Fermé, Christophe, Carde, Patrice, Hermine, Olivier, Pendeven, Catherine Le-, Amiel, Corinne, Taoufik, Yassine, Alcaïs, Alexandre, Theodorou, Ioannis, Besson, Caroline, Abel, Laurent
Pubblicazione 2014

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

di Alter, Andrea, de Léséleuc, Louis, Van Thuc, Nguyen, Thai, Vu Hong, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Cardoso, Cynthia Chester, Grant, Audrey Virginia, Abel, Laurent, Moraes, Milton Ozório, Alcaïs, Alexandre, Schurr, Erwin
Pubblicazione 2009

Human Leukocyte Antigen Class I Region Single-Nucleotide Polymorphisms are Associated with Leprosy Susceptibility in Vietnam and India

di Alter, Andrea, Huong, Nguyen Thu, Singh, Meenakshi, Orlova, Marianna, Van Thuc, Nguyen, Katoch, Kiran, Gao, Xiaojiang, Thai, Vu Hong, Ba, Nguyen Ngoc, Carrington, Mary, Abel, Laurent, Mehra, Narinder, Alcaïs, Alexandre, Schurr, Erwin
Pubblicazione 2011