Human genetics of infectious diseases: between proof of principle and paradigm

Por Alcaïs, Alexandre, Abel, Laurent, Casanova, Jean-Laurent
Publicado em 2009

Tuberculosis in children and adults: two distinct genetic diseases

Por Alcaïs, Alexandre, Fieschi, Claire, Abel, Laurent, Casanova, Jean-Laurent
Publicado em 2005

Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

Por Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Publicado em 2005

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction

Por Fava, Vinicius M., Sales-Marques, Carolinne, Alcaïs, Alexandre, Moraes, Milton O., Schurr, Erwin
Publicado no Front Immunol (2017)

Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes

Por Fava, Vinicius M., Cobat, Aurélie, Gzara, Chaïma, Alcaïs, Alexandre, Abel, Laurent, Schurr, Erwin
Publicado no Proc Natl Acad Sci U S A (2020)

Evaluation of Approaches to Identify Associated SNPs That Explain the Linkage Evidence in Nuclear Families with Affected Siblings

Por Chen, Ming-Huei, Van Eerdewegh, Paul, Vincent, Quentin B., Alcais, Alexandre, Abel, Laurent, Dupuis, Josée
Publicado em 2010

Highly Significant Association between Two Common Single Nucleotide Polymorphisms in CORIN Gene and Preeclampsia in Caucasian Women

Por Stepanian, Alain, Alcaïs, Alexandre, de Prost, Dominique, Tsatsaris, Vassilis, Dreyfus, Michel, Treluyer, Jean-Marc, Mandelbrot, Laurent
Publicado no PLoS One (2014)

Tuberculin Skin Test Reactivity Is Dependent on Host Genetic Background in Colombian Tuberculosis Household Contacts

Por Cobat, Aurélie, Barrera, Luis F., Henao, Hanna, Arbeláez, Patricia, Abel, Laurent, García, Luis F., Schurr, Erwin, Alcaïs, Alexandre
Publicado em 2012

Somatic Hypermutation at A/T-Rich Oligonucleotide Substrates Shows Different Strand Polarities in Ung-Deficient or -Proficient Backgrounds

Por Zivojnovic, Marija, Delbos, Frédéric, Girelli Zubani, Giulia, Julé, Amélie, Alcais, Alexandre, Weill, Jean-Claude, Reynaud, Claude-Agnès, Storck, Sébastien
Publicado em 2014

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy

Por Fava, Vinicius M., Manry, Jérémy, Cobat, Aurélie, Orlova, Marianna, Van Thuc, Nguyen, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Publicado no PLoS Negl Trop Dis (2016)

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

Por Dallmann-Sauer, Monica, Fava, Vinicius M., Gzara, Chaïma, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Schurr, Erwin
Publicado no PLoS Pathog (2020)

Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

Por Manry, Jeremy, Vincent, Quentin B., Johnson, Christian, Chrabieh, Maya, Lorenzo, Lazaro, Theodorou, Ioannis, Ardant, Marie-Françoise, Marion, Estelle, Chauty, Annick, Marsollier, Laurent, Abel, Laurent, Alcaïs, Alexandre
Publicado no Commun Biol (2020)

Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases

Por Gaschignard, Jean, Grant, Audrey Virginia, Thuc, Nguyen Van, Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Schurr, Erwin, Alcaïs, Alexandre
Publicado no PLoS Negl Trop Dis (2016)

Gene Set Signature of Reversal Reaction Type I in Leprosy Patients

Por Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Publicado em 2013

Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

Por Belkadi, Aziz, Pedergnana, Vincent, Cobat, Aurélie, Itan, Yuval, Vincent, Quentin B., Abhyankar, Avinash, Shang, Lei, El Baghdadi, Jamila, Bousfiha, Aziz, Alcais, Alexandre, Boisson, Bertrand, Casanova, Jean-Laurent, Abel, Laurent
Publicado no Proc Natl Acad Sci U S A (2016)

Family-based genome-wide association study of leprosy in Vietnam

Por Gzara, Chaima, Dallmann-Sauer, Monica, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Fava, Vinicius M., Bihoreau, Marie-Thérèse, Boland, Anne, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin, Cobat, Aurélie
Publicado no PLoS Pathog (2020)

PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages

Por de Léséleuc, Louis, Orlova, Marianna, Cobat, Aurelie, Girard, Manon, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Truman, Richard, Spencer, John S., Adams, Linda, Thai, Vu Hong, Alcais, Alexandre, Schurr, Erwin
Publicado em 2013

Combined Linkage and Association Studies Show that HLA Class II Variants Control Levels of Antibodies against Epstein-Barr Virus Antigens

Por Pedergnana, Vincent, Syx, Laurène, Cobat, Aurélie, Guergnon, Julien, Brice, Pauline, Fermé, Christophe, Carde, Patrice, Hermine, Olivier, Pendeven, Catherine Le-, Amiel, Corinne, Taoufik, Yassine, Alcaïs, Alexandre, Theodorou, Ioannis, Besson, Caroline, Abel, Laurent
Publicado em 2014

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

Por Alter, Andrea, de Léséleuc, Louis, Van Thuc, Nguyen, Thai, Vu Hong, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Cardoso, Cynthia Chester, Grant, Audrey Virginia, Abel, Laurent, Moraes, Milton Ozório, Alcaïs, Alexandre, Schurr, Erwin
Publicado em 2009

Human Leukocyte Antigen Class I Region Single-Nucleotide Polymorphisms are Associated with Leprosy Susceptibility in Vietnam and India

Por Alter, Andrea, Huong, Nguyen Thu, Singh, Meenakshi, Orlova, Marianna, Van Thuc, Nguyen, Katoch, Kiran, Gao, Xiaojiang, Thai, Vu Hong, Ba, Nguyen Ngoc, Carrington, Mary, Abel, Laurent, Mehra, Narinder, Alcaïs, Alexandre, Schurr, Erwin
Publicado em 2011