Human genetics of infectious diseases: between proof of principle and paradigm

by Alcaïs, Alexandre, Abel, Laurent, Casanova, Jean-Laurent
Published 2009

Tuberculosis in children and adults: two distinct genetic diseases

by Alcaïs, Alexandre, Fieschi, Claire, Abel, Laurent, Casanova, Jean-Laurent
Published 2005

Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

by Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Published 2005

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction

by Fava, Vinicius M., Sales-Marques, Carolinne, Alcaïs, Alexandre, Moraes, Milton O., Schurr, Erwin
Published in Front Immunol (2017)

Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes

by Fava, Vinicius M., Cobat, Aurélie, Gzara, Chaïma, Alcaïs, Alexandre, Abel, Laurent, Schurr, Erwin
Published in Proc Natl Acad Sci U S A (2020)

Evaluation of Approaches to Identify Associated SNPs That Explain the Linkage Evidence in Nuclear Families with Affected Siblings

by Chen, Ming-Huei, Van Eerdewegh, Paul, Vincent, Quentin B., Alcais, Alexandre, Abel, Laurent, Dupuis, Josée
Published 2010

Highly Significant Association between Two Common Single Nucleotide Polymorphisms in CORIN Gene and Preeclampsia in Caucasian Women

by Stepanian, Alain, Alcaïs, Alexandre, de Prost, Dominique, Tsatsaris, Vassilis, Dreyfus, Michel, Treluyer, Jean-Marc, Mandelbrot, Laurent
Published in PLoS One (2014)

Tuberculin Skin Test Reactivity Is Dependent on Host Genetic Background in Colombian Tuberculosis Household Contacts

by Cobat, Aurélie, Barrera, Luis F., Henao, Hanna, Arbeláez, Patricia, Abel, Laurent, García, Luis F., Schurr, Erwin, Alcaïs, Alexandre
Published 2012

Somatic Hypermutation at A/T-Rich Oligonucleotide Substrates Shows Different Strand Polarities in Ung-Deficient or -Proficient Backgrounds

by Zivojnovic, Marija, Delbos, Frédéric, Girelli Zubani, Giulia, Julé, Amélie, Alcais, Alexandre, Weill, Jean-Claude, Reynaud, Claude-Agnès, Storck, Sébastien
Published 2014

A Missense LRRK2 Variant Is a Risk Factor for Excessive Inflammatory Responses in Leprosy

by Fava, Vinicius M., Manry, Jérémy, Cobat, Aurélie, Orlova, Marianna, Van Thuc, Nguyen, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Published in PLoS Negl Trop Dis (2016)

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

by Dallmann-Sauer, Monica, Fava, Vinicius M., Gzara, Chaïma, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Alcaïs, Alexandre, Abel, Laurent, Cobat, Aurélie, Schurr, Erwin
Published in PLoS Pathog (2020)

Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

by Manry, Jeremy, Vincent, Quentin B., Johnson, Christian, Chrabieh, Maya, Lorenzo, Lazaro, Theodorou, Ioannis, Ardant, Marie-Françoise, Marion, Estelle, Chauty, Annick, Marsollier, Laurent, Abel, Laurent, Alcaïs, Alexandre
Published in Commun Biol (2020)

Pauci- and Multibacillary Leprosy: Two Distinct, Genetically Neglected Diseases

by Gaschignard, Jean, Grant, Audrey Virginia, Thuc, Nguyen Van, Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Thai, Vu Hong, Abel, Laurent, Schurr, Erwin, Alcaïs, Alexandre
Published in PLoS Negl Trop Dis (2016)

Gene Set Signature of Reversal Reaction Type I in Leprosy Patients

by Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Published 2013

Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

by Belkadi, Aziz, Pedergnana, Vincent, Cobat, Aurélie, Itan, Yuval, Vincent, Quentin B., Abhyankar, Avinash, Shang, Lei, El Baghdadi, Jamila, Bousfiha, Aziz, Alcais, Alexandre, Boisson, Bertrand, Casanova, Jean-Laurent, Abel, Laurent
Published in Proc Natl Acad Sci U S A (2016)

Family-based genome-wide association study of leprosy in Vietnam

by Gzara, Chaima, Dallmann-Sauer, Monica, Orlova, Marianna, Van Thuc, Nguyen, Thai, Vu Hong, Fava, Vinicius M., Bihoreau, Marie-Thérèse, Boland, Anne, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin, Cobat, Aurélie
Published in PLoS Pathog (2020)

PARK2 Mediates Interleukin 6 and Monocyte Chemoattractant Protein 1 Production by Human Macrophages

by de Léséleuc, Louis, Orlova, Marianna, Cobat, Aurelie, Girard, Manon, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Truman, Richard, Spencer, John S., Adams, Linda, Thai, Vu Hong, Alcais, Alexandre, Schurr, Erwin
Published 2013

Combined Linkage and Association Studies Show that HLA Class II Variants Control Levels of Antibodies against Epstein-Barr Virus Antigens

by Pedergnana, Vincent, Syx, Laurène, Cobat, Aurélie, Guergnon, Julien, Brice, Pauline, Fermé, Christophe, Carde, Patrice, Hermine, Olivier, Pendeven, Catherine Le-, Amiel, Corinne, Taoufik, Yassine, Alcaïs, Alexandre, Theodorou, Ioannis, Besson, Caroline, Abel, Laurent
Published 2014

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

by Alter, Andrea, de Léséleuc, Louis, Van Thuc, Nguyen, Thai, Vu Hong, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Cardoso, Cynthia Chester, Grant, Audrey Virginia, Abel, Laurent, Moraes, Milton Ozório, Alcaïs, Alexandre, Schurr, Erwin
Published 2009

Human Leukocyte Antigen Class I Region Single-Nucleotide Polymorphisms are Associated with Leprosy Susceptibility in Vietnam and India

by Alter, Andrea, Huong, Nguyen Thu, Singh, Meenakshi, Orlova, Marianna, Van Thuc, Nguyen, Katoch, Kiran, Gao, Xiaojiang, Thai, Vu Hong, Ba, Nguyen Ngoc, Carrington, Mary, Abel, Laurent, Mehra, Narinder, Alcaïs, Alexandre, Schurr, Erwin
Published 2011