Preventive effect of malotilate on carbon tetrachloride-induced liver damage and collagen accumulation in the rat.

Por Ala-Kokko, L, Stenbäck, F, Ryhänen, L
Publicado em 1987

Dexamethasone modulates the metabolism of type IV collagen and fibronectin in human basement-membrane-forming fibrosarcoma (HT-1080) cells.

Por Oikarinen, A, Salo, T, Ala-Kokko, L, Tryggvason, K
Publicado em 1987

Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia.

Por Ala-Kokko, L, Baldwin, C T, Moskowitz, R W, Prockop, D J
Publicado em 1990

Structure of cDNA clones coding for the entire prepro alpha 1 (III) chain of human type III procollagen. Differences in protein structure from type I procollagen and conservation o...

Por Ala-Kokko, L, Kontusaari, S, Baldwin, C T, Kuivaniemi, H, Prockop, D J
Publicado em 1989

Serum concentrations of the N-terminal propeptide of type III procollagen and two type IV collagen fragments and gene expression of the respective collagen types in liver in rats w...

Por Savolainen, E R, Brocks, D, Ala-Kokko, L, Kivirikko, K I
Publicado em 1988

Sensitivity of conformation sensitive gel electrophoresis in detecting mutations in Marfan syndrome and related conditions

Por Korkko, J, Kaitila, I, Lonnqvist, L, Peltonen, L, Ala-Kokko, L
Publicado em 2002

Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.

Por Vandenberg, P, Khillan, J S, Prockop, D J, Helminen, H, Kontusaari, S, Ala-Kokko, L
Publicado em 1991

Gene expression of type I, III and IV collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat.

Por Ala-Kokko, L, Pihlajaniemi, T, Myers, J C, Kivirikko, K I, Savolainen, E R
Publicado em 1987

Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse.

Por Vikkula, M, Metsäranta, M, Syvänen, A C, Ala-Kokko, L, Vuorio, E, Peltonen, L
Publicado em 1992

Analysis of the COL1A1 and COL1A2 genes by PCR amplification and scanning by conformation-sensitive gel electrophoresis identifies only COL1A1 mutations in 15 patients with osteoge...

Por Körkkö, J, Ala-Kokko, L, De Paepe, A, Nuytinck, L, Earley, J, Prockop, D J
Publicado em 1998

COL9A3: A third locus for multiple epiphyseal dysplasia.

Por Paassilta, P, Lohiniva, J, Annunen, S, Bonaventure, J, Le Merrer, M, Pai, L, Ala-Kokko, L
Publicado em 1999

Sequence variations in the collagen IX and XI genes are associated with degenerative lumbar spinal stenosis

Por Noponen-Hietala, N, Kyllonen, E, Mannikko, M, Ilkko, E, Karppinen, J, Ott, J, Ala-Kokko, L
Publicado em 2003

Mutation in type II procollagen (COL2A1) that substitutes aspartate for glycine alpha 1-67 and that causes cataracts and retinal detachment: evidence for molecular heterogeneity in...

Por Körkkö, J, Ritvaniemi, P, Haataja, L, Kääriäinen, H, Kivirikko, K I, Prockop, D J, Ala-Kokko, L
Publicado em 1993

Synthesis of recombinant human procollagen II in a stably transfected tumour cell line (HT1080).

Por Fertala, A, Sieron, A L, Ganguly, A, Li, S W, Ala-Kokko, L, Anumula, K R, Prockop, D J
Publicado em 1994

Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1...

Por Ala-Kokko, L, Kvist, A P, Metsäranta, M, Kivirikko, K I, de Crombrugghe, B, Prockop, D J, Vuorio, E
Publicado em 1995

Lack of a phenotype in transgenic mice aberrantly expressing COL2A1 mRNA because of highly selective post-transcriptional down-regulation.

Por Yuan, C M, Ala-Kokko, L, Le Guellec, D, Franc, S, Fertala, A, Khillan, J S, Sokolov, B P, Prockop, D J
Publicado em 2000

Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy).

Por Ahmad, N N, Ala-Kokko, L, Knowlton, R G, Jimenez, S A, Weaver, E J, Maguire, J I, Tasman, W, Prockop, D J
Publicado em 1991

Substitution of aspartic acid for glycine at position 310 in type II collagen produces achondrogenesis II, and substitution of serine at position 805 produces hypochondrogenesis: a...

Por Bonaventure, J, Cohen-Solal, L, Ritvaniemi, P, Van Maldergem, L, Kadhom, N, Delezoide, A L, Maroteaux, P, Prockop, D J, Ala-Kokko, L
Publicado em 1995

An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice...

Por Helminen, H J, Kiraly, K, Pelttari, A, Tammi, M I, Vandenberg, P, Pereira, R, Dhulipala, R, Khillan, J S, Ala-Kokko, L, Hume, E L
Publicado em 1993

A recurrent R718W mutation in COMP results in multiple epiphyseal dysplasia with mild myopathy: clinical and pathogenetic overlap with collagen IX mutations

Por Jakkula, E, Lohiniva, J, Capone, A, Bonafe, L, Marti, M, Schuster, V, Giedion, A, Eich, G, Boltshauser, E, Ala-Kokko, L, Superti-Furga, A
Publicado em 2003